COMPARATIVE ATHEROSCLEROSIS

Comparative Severity of Atherosclerosis in Costa

The present study is concerned with the comparative severity of aortic atherosclerosis in specimens obtained from 941 neeropsies performed in low-income Costa Ricans, Guatemalans, and New Orleans whites. The findings indicate geographic differences in the severity of atherosclerosis after the age of 30 years. The dietary habits, serum cholesterol, and lipoprotein patterns of similar populations...

Atherosclerosis in rheumatoid arthritis versus diabetes: a comparative study.

OBJECTIVE The extent to which atherosclerosis is accelerated in chronic inflammatory diseases is not established. We compared preclinical atherosclerosis in rheumatoid arthritis with diabetes mellitus, a known coronary heart disease equivalent. METHODS AND RESULTS Endothelial function, arterial stiffness, carotid intima-media thickness, and analysis of atheromatous plaques were examined in 84...

A comparative study of cerebral atherosclerosis in males and females.

An evaluation of the influence of sex upon cerebral atherosclerosis was carried out in 5,033 consecutive autopsies studied by a special well-standardized coding technique. A sex difference in frequency of cerebral atherosclerosis appears from the fourth to the sixth decade. During this period the percentage of female cases with no atherosclerosis lags behind the percentage of male cases by a 15...

Vascular Smooth Muscle Cells and the Comparative Pathology of Atherosclerosis

Comparative genetics of atherosclerosis and restenosis: exploration with mouse models.

Ischemic heart disease is a consequence of coronary atherosclerosis. In addition to coronary bypass surgery, a common and often successful treatment is angioplasty, expanding the internal lumen of the coronary artery with a balloon. However, 30% to 50% of angioplasty patients soon develop significant restenosis, a narrowing of the artery through migration and growth of smooth muscle cells. Sten...